Rhabdovirus

Rabies virus (RABV) is a member of the family Rhabdovirus (Rhabdoviridae). Rabies virus has a broad host range with the capacity to infect almost all mammals. Untreated rabies infections are nearly 100% fatal, causing 50,000 to 60,000 human deaths annually and significantly affecting animal populations. The rabies virus glycoprotein (RABV-G) is the only surface-exposed protein on the virus and is the target of vaccine-elicited neutralizing antibodies.